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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM522459 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | HTRF Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Wang, X; Li, Y; Qi, C; Wu, L; Yao, W; Zhu, W Fused pyrazine derivatives as A2A / A2B inhibitors US Patent US11161850 Publication Date 11/2/2021 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
| ||
| BDBM522459 | |||
| n/a | |||
| Name | BDBM522459 | ||
| Synonyms: | US11161850, Example 2 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H22N8O | ||
| Mol. Mass. | 414.4631 | ||
| SMILES | CCCn1nccc1-c1c(nc(N)c2cc(nn12)C(=O)NCC)-c1cccc(c1)C#N |(5.02,3.09,;3.53,3.49,;2.44,2.4,;.95,2.8,;.48,4.26,;-1.06,4.26,;-1.54,2.8,;-.29,1.9,;-.29,.36,;-1.63,-.41,;-1.63,-1.95,;-.29,-2.72,;-.29,-4.26,;1.04,-1.95,;2.5,-2.43,;3.41,-1.18,;2.5,.06,;1.04,-.41,;4.95,-1.18,;5.72,.15,;5.72,-2.52,;7.21,-2.12,;8.3,-3.21,;-2.96,.36,;-2.96,1.9,;-4.3,2.67,;-5.63,1.9,;-5.63,.36,;-4.3,-.41,;-6.96,-.41,;-8.3,-1.18,)| | ||
| Structure | 
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