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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM522570 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | HTRF Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Wang, X; Li, Y; Qi, C; Wu, L; Yao, W; Zhu, W Fused pyrazine derivatives as A2A / A2B inhibitors US Patent US11161850 Publication Date 11/2/2021 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
| ||
| BDBM522570 | |||
| n/a | |||
| Name | BDBM522570 | ||
| Synonyms: | US11161850, Example 34 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H21N7O2 | ||
| Mol. Mass. | 451.4799 | ||
| SMILES | CC(O)c1nc(C)oc1-c1c(nc(N)c2cc(Cc3ccccn3)nn12)-c1cccc(c1)C#N |(2.87,.66,;2.55,2.16,;3.69,3.19,;1.09,2.64,;.61,4.1,;-.93,4.1,;-1.84,5.35,;-1.41,2.64,;-.16,1.73,;-.16,.19,;-1.49,-.58,;-1.49,-2.12,;-.16,-2.89,;-.16,-4.43,;1.17,-2.12,;2.64,-2.59,;3.54,-1.35,;5.08,-1.35,;5.85,-2.68,;5.08,-4.01,;5.85,-5.35,;7.39,-5.35,;8.16,-4.01,;7.39,-2.68,;2.64,-.1,;1.17,-.58,;-2.83,.19,;-2.83,1.73,;-4.16,2.5,;-5.5,1.73,;-5.5,.19,;-4.16,-.58,;-6.83,-.58,;-8.16,-1.35,)| | ||
| Structure | 
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