Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM522671 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | HTRF Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Wang, X; Li, Y; Qi, C; Wu, L; Yao, W; Zhu, W Fused pyrazine derivatives as A2A / A2B inhibitors US Patent US11161850 Publication Date 11/2/2021 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
| ||
| BDBM522671 | |||
| n/a | |||
| Name | BDBM522671 | ||
| Synonyms: | US11161850, Example 44 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H18N8 | ||
| Mol. Mass. | 418.4533 | ||
| SMILES | Cc1cnccc1-c1c(nc(N)c2nc(Cc3ccccn3)nn12)-c1cccc(c1)C#N |(2.51,2,;1.17,2.77,;1.17,4.31,;-.16,5.08,;-1.49,4.31,;-1.49,2.77,;-.16,2,;-.16,.46,;-1.49,-.31,;-1.49,-1.85,;-.16,-2.62,;-.16,-4.16,;1.17,-1.85,;2.64,-2.33,;3.54,-1.08,;5.08,-1.08,;5.85,-2.41,;5.08,-3.75,;5.85,-5.08,;7.39,-5.08,;8.16,-3.75,;7.39,-2.41,;2.64,.17,;1.17,-.31,;-2.83,.46,;-2.83,2,;-4.16,2.77,;-5.5,2,;-5.5,.46,;-4.16,-.31,;-6.83,-.31,;-8.16,-1.08,)| | ||
| Structure | 
| ||