| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM454194 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays |
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| EC50 | 170±n/a nM |
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| Citation |  Wurtz, NR; Shirude, PS; Viet, AQ Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists US Patent US11186544 Publication Date 11/30/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM454194 |
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| n/a |
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| Name | BDBM454194 |
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| Synonyms: | US10717708, Example 129 | US11186544, Example 129 | US11530183, Example 129 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25F3N4O3 |
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| Mol. Mass. | 498.4969 |
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| SMILES | CCOc1ncccc1-c1ccc(cc1)N1CCC[C@@H](NC(=O)Nc2ccc(cc2)C(F)(F)F)C1=O |r| |
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| Structure | 
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