| Reaction Details |
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 | Report a problem with these data |
| Target | Triple specificity protein phosphatase PtpB |
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| Ligand | BDBM50544436 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 60.0±9 nM |
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| Citation |  Zhang, Z; Ruddraraju, KV N-aryl oxamic acids US Patent US11192850 Publication Date 12/7/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Triple specificity protein phosphatase PtpB |
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| Name: | Triple specificity protein phosphatase PtpB |
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| Synonyms: | PTPB_MYCTU | Phosphoinositide phosphatase | Protein-serine/threonine phosphatase | Protein-tyrosine phosphatase B | TSP PTP | mptpB | ptpB |
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| Type: | Protein |
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| Mol. Mass.: | 30152.45 |
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| Organism: | n/a |
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| Description: | I6WXK4 |
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| Residue: | 276 |
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| Sequence: | MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSRE
VARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSIND
AATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGL
DRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLA
AARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
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| BDBM50544436 |
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| n/a |
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| Name | BDBM50544436 |
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| Synonyms: | CHEMBL4649291 | US11192850, Entry 4p |
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| Type | Small organic molecule |
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| Emp. Form. | C18H9F6NO3 |
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| Mol. Mass. | 401.2594 |
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| SMILES | OC(=O)C(=O)Nc1ccc(cc1)C#Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F |
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| Structure | 
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