| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Polyamine deacetylase HDAC10 |
|---|
| Ligand | BDBM323709 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | IC50 Assay |
|---|
| IC50 | 2.00±n/a nM |
|---|
| Citation |  Hooker, J; Wang, C; Strebl-Bantillo, MG HDAC6 inhibitors and imaging agents US Patent US11207431 Publication Date 12/28/2021 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Polyamine deacetylase HDAC10 |
|---|
| Name: | Polyamine deacetylase HDAC10 |
|---|
| Synonyms: | HD10 | HDA10_HUMAN | HDAC10 | Histone deacetylase | Histone deacetylase 10 | Human HDAC10 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 71431.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q969S8 |
|---|
| Residue: | 669 |
|---|
| Sequence: | MGTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEEL
GLVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTG
AVQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQ
YLFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVA
AFLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAV
LEGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQ
DVTAVPMSPSSHSPEGRPPPLLPGGPVCKAAASAPSSLLDQPCLCPAPSVRTAVALTTPD
ITLVLPPDVIQQEASALREETEAWARPHESLAREEALTALGKLLYLLDGMLDGQVNSGIA
ATPASAAAATLDVAVRRGLSHGAQRLLCVALGQLDRPPDLAHDGRSLWLNIRGKEAAALS
MFHVSTPLPVMTGGFLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAAMLRGL
AGGRVLALLEENSTPQLAGILARVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM
LQCHPHLVA
|
|
|
|---|
| BDBM323709 |
|---|
| n/a |
|---|
| Name | BDBM323709 |
|---|
| Synonyms: | US10188756, Compound CN133 | US11207431, Martinostat |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H30N2O2 |
|---|
| Mol. Mass. | 354.4858 |
|---|
| SMILES | CN(Cc1ccc(\C=C\C(=O)NO)cc1)CC12CC3CC(CC(C3)C1)C2 |TLB:19:20:24:18.23.17,23:18:25:24.22.21,23:22:25:18.19.17,THB:19:18:24:25.20.21| |
|---|
| Structure | 
|
|---|
Search and Browse
