| Reaction Details |
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 | Report a problem with these data |
| Target | Monocarboxylate transporter 1 |
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| Ligand | BDBM356770 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Activity Assay 4 |
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| IC50 | 72000±n/a nM |
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| Citation |  Parnell, KM; McCall, J; Romero, D Heterocyclic inhibitors of MCT4 US Patent US11292767 Publication Date 4/5/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Monocarboxylate transporter 1 |
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| Name: | Monocarboxylate transporter 1 |
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| Synonyms: | MCT 1 | MCT1 | MOT1_HUMAN | Monocarboxylate transporter 1 | SLC16A1 | Solute carrier family 16 member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53956.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1451367 |
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| Residue: | 500 |
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| Sequence: | MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSW
ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIG
GLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLI
LGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQ
EKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAF
LLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYA
GFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYK
YTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA
AESPDQKDTDGGPKEEESPV
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| BDBM356770 |
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| n/a |
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| Name | BDBM356770 |
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| Synonyms: | US10214492, Example 134 | US11292767, Example 134 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H26ClN3O4 |
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| Mol. Mass. | 431.913 |
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| SMILES | CC(C)Cc1ncc(o1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl |
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| Structure | 
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