| Reaction Details |
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 | Report a problem with these data |
| Target | Monocarboxylate transporter 4 |
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| Ligand | BDBM356912 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Activity Assay 3 |
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| IC50 | 2.20±n/a nM |
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| Citation |  Parnell, KM; McCall, J; Romero, D Heterocyclic inhibitors of MCT4 US Patent US11292767 Publication Date 4/5/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Monocarboxylate transporter 4 |
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| Name: | Monocarboxylate transporter 4 |
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| Synonyms: | MCT 4 | MCT3 | MCT4 | MOT4_HUMAN | SLC16A3 | Solute carrier family 16 member 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49474.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104604 |
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| Residue: | 465 |
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| Sequence: | MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDT
AWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGV
ITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGF
LILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVL
GLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSF
SMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVL
LMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPE
VAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
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| BDBM356912 |
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| n/a |
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| Name | BDBM356912 |
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| Synonyms: | US10214492, Example 263 | US11292767, Example 263 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31N5O4 |
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| Mol. Mass. | 477.5554 |
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| SMILES | CC[C@@](C)(OCc1cc(-c2cccc(OCC(C)C)c2)n(n1)-c1cccc2nnn(C)c12)C(O)=O |r| |
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| Structure | 
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