| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucan 1,4-alpha-glucosidase |
|---|
| Ligand | BDBM546721 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Property Evaluation 3 |
|---|
| IC50 | 65±1 nM |
|---|
| Citation |  Na, DH; Kang, KP; Jun, JH; Go, G; Na, HJ; Kang, SJ; Na, YH; Yoon, SJ; Na, SJ Composition for inhibiting growth of SARS-CoV-2 and method of preparing the same US Patent US11292789 Publication Date 4/5/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucan 1,4-alpha-glucosidase |
|---|
| Name: | Glucan 1,4-alpha-glucosidase |
|---|
| Synonyms: | 1,4-alpha-D-glucan glucohydrolase | Glucan 1,4-alpha-glucosidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 58125.45 |
|---|
| Organism: | Shiitake mushroom |
|---|
| Description: | A0A1Q3E5G6 |
|---|
| Residue: | 534 |
|---|
| Sequence: | MLSNSANDYIQREGPLAQAGLLANIGPNGNQASAAAPGIAIASPSTSNPNYLYSWTRDAA
LVFKVIVDHYARSPAPRDLSLRTLIDSYADAQSRLQEVENPSGNITTGGLGEPKFNIDLT
AFTGSWDLNAMALLDLDYVADNWNKTGFDLWEEVSSSSFWTTAAQHRALRQGAELAKTLS
KDDLAESYSTQADNALCFLQSYWNPNGSYITSNTGGGRSGIDANSILASIHSFDPSAGCD
ALTFQPCSDKALSNLKAYVDSFKTIYGINEGFSENEAIATGRYPEDIYMEGNPWYLTTFA
VAEQLYDSLSVWDAQGSLQITPVSLSFFQQFSSNVQTGNYGADSQTYGTLTSKIRAFADG
FIAVNGNYTPESGSLAEQYGKDDGKPTSARDLTWSYASAITSFLAHDGIVPTPWGAQGLQ
IRRDANGHCISNPGPMSEIVFEVERNTLYGENVYITGSIGQLGDWEPANAVRLEPKNYPS
WTVRIEIPASTTFSYKYIVQDQRSGQVTWENDPNHEVASPFKGQSVVLSDTWHD
|
|
|
|---|
| BDBM546721 |
|---|
| n/a |
|---|
| Name | BDBM546721 |
|---|
| Synonyms: | US11292789, MDPX-V2021 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H24N2O4 |
|---|
| Mol. Mass. | 368.4263 |
|---|
| SMILES | COc1ccc(c(COC(C)(C)C)c1)-n1cnc2ccc(OC)cc2c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
