| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transthyretin |
|---|
| Ligand | BDBM50355116 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence Polarization Binding Assay |
|---|
| IC50 | 4786±n/a nM |
|---|
| Citation |  Graef, IA; Alhamadsheh, MM Identification of stabilizers of multimeric proteins US Patent US11337935 Publication Date 5/24/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transthyretin |
|---|
| Name: | Transthyretin |
|---|
| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 15884.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P02766 |
|---|
| Residue: | 147 |
|---|
| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
|
|
|
|---|
| BDBM50355116 |
|---|
| n/a |
|---|
| Name | BDBM50355116 |
|---|
| Synonyms: | CHEMBL493923 | US10278929, Compound 22 | US11337935, Compound 22 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H14N2O2S2 |
|---|
| Mol. Mass. | 354.446 |
|---|
| SMILES | Oc1ccccc1C1NC(=O)C(C#N)=C(SCc2ccccc2)S1 |t:14| |
|---|
| Structure | 
|
|---|
Search and Browse
