| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl2-associated agonist of cell death |
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| Ligand | BDBM552910 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| Kd | >100±n/a nM |
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| Citation |  Pinchman, JR; Huang, PQ; Bunker, KD; Sit, RK; Samatar, AA Benzamide compounds US Patent US11344546 Publication Date 5/31/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bcl2-associated agonist of cell death |
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| Name: | Bcl2-associated agonist of cell death |
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| Synonyms: | BAD | BAD_HUMAN | BBC6 | BCL2L8 | Bcl-2-binding component 6 | Bcl-2-like protein 8 | Bcl-XL/Bcl-2-associated death promoter | Bcl2 antagonist of cell death | Bcl2-L-8 | Bcl2-antagonist of cell death (BAD) |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18393.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_478760 |
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| Residue: | 168 |
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| Sequence: | MFQIPEFEPSEQEDSSSAERGLGPSPAGDGPSGSGKHHRQAPGLLWDASHQQEQPTSSSH
HGGAGAVEIRSRHSSYPAGTEDDEGMGEEPSPFRGRSRSAPPNLWAAQRYGRELRRMSDE
FVDSFKKGLPRPKSAGTATQMRQSSSWTRVFQSWWDRNLGRGSSAPSQ
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| BDBM552910 |
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| n/a |
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| Name | BDBM552910 |
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| Synonyms: | 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-dimethyl-2-(3-methylbicyclo[1.1.1]pentan-1-yl)cyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((4-(((4-fluoro-1-methylpiperidin-4-yl)methyl)amino)-3-nitrophenyl)sulfonyl)benzamide | US11318134, Example 13 | US11344546, Example 13 | US11590126, Example 13 |
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| Type | Small organic molecule |
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| Emp. Form. | C46H57FN8O6S |
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| Mol. Mass. | 869.058 |
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| SMILES | CN1CCC(F)(CNc2ccc(cc2[N+]([O-])=O)S(=O)(=O)NC(=O)c2ccc(cc2Oc2cnc3[nH]ccc3c2)N2CCN(CC3=C(CC(C)(C)CC3)C34CC(C)(C3)C4)CC2)CC1 |t:48| |
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| Structure | 
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