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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559667 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.34±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559667 | |||
| n/a | |||
| Name | BDBM559667 | ||
| Synonyms: | WO2022109117, Example 12 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H41N3O4S | ||
| Mol. Mass. | 491.686 | ||
| SMILES | C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(CCCCCC(=O)N12)c3 |wD:1.0,3.3,14.14,17.16,11.34,(17.35,6.53,;16.85,5.1,;17.71,3.85,;16.79,2.65,;17.22,1.2,;18.69,.85,;19.05,2.32,;18.34,-.63,;20.17,.5,;20.6,-.96,;21.21,1.6,;15.36,3.15,;14.75,1.71,;13.61,.63,;12.06,.34,;11.8,1.85,;10.39,2.4,;9.13,1.51,;9.42,-.03,;10.84,-.6,;7.92,2.59,;6.37,2.51,;5.46,3.74,;6.1,5.12,;7.63,5.32,;8.33,6.72,;9.48,7.75,;10.94,8.19,;12.48,8.05,;13.85,7.35,;14.88,6.19,;16.19,6.95,;15.39,4.67,;8.48,4.04,)| | ||
| Structure | 
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