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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559669 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.18±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559669 | |||
| n/a | |||
| Name | BDBM559669 | ||
| Synonyms: | WO2022109117, Example 14 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H37N3O5S | ||
| Mol. Mass. | 479.633 | ||
| SMILES | C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCC(=O)N12)c3 |wU:14.14,17.16,wD:1.0,3.3,11.33,(16.68,5.97,;16.31,4.49,;17.28,3.33,;16.47,2.04,;17.03,.63,;18.54,.42,;18.75,1.92,;18.32,-1.09,;20.04,.2,;20.6,-1.21,;20.98,1.39,;15,2.42,;14.51,.92,;13.48,-.31,;11.86,-.64,;10.53,-1.48,;9.11,-.9,;8.9,.66,;10.19,1.5,;11.57,.86,;7.79,1.85,;6.23,1.94,;5.51,3.29,;6.25,4.61,;7.8,4.57,;8.68,5.84,;9.98,6.67,;11.51,6.83,;12.99,6.38,;14.19,5.37,;15.38,6.3,;14.9,3.93,;8.53,3.21,)| | ||
| Structure | 
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