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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559673 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.14±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM559673 | |||
| n/a | |||
| Name | BDBM559673 | ||
| Synonyms: | WO2022109117, Example 18 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H37N3O6S | ||
| Mol. Mass. | 495.632 | ||
| SMILES | C[C@@H]1C[C@H](NS(=O)(=O)N(C)C)[C@@H]2CO[C@H]3CC[C@H](CC3)c3cccc(OCCCOC(=O)N12)c3 |wD:3.3,14.14,17.16,11.34,1.0,(17.24,6.51,;16.73,5.07,;17.59,3.82,;16.67,2.61,;17.1,1.15,;18.58,.8,;18.94,2.28,;18.23,-.68,;20.06,.45,;20.5,-1.01,;21.11,1.55,;15.23,3.12,;14.63,1.66,;13.48,.58,;11.93,.3,;11.66,1.81,;10.25,2.36,;8.98,1.46,;9.27,-.08,;10.7,-.66,;7.77,2.55,;6.21,2.47,;5.3,3.7,;5.95,5.09,;7.48,5.29,;8.19,6.69,;9.33,7.73,;10.8,8.17,;12.34,8.03,;13.72,7.33,;14.75,6.16,;16.07,6.92,;15.27,4.64,;8.33,4.01,)| | ||
| Structure | 
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