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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559700 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.32±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559700 | |||
| n/a | |||
| Name | BDBM559700 | ||
| Synonyms: | WO2022109117, Example 45 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H33FN2O6S | ||
| Mol. Mass. | 484.581 | ||
| SMILES | C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3cc(F)cc(OCCCOC(=O)N12)c3 |wD:1.0,3.3,9.33,(17.42,6.56,;16.91,5.12,;17.78,3.87,;16.85,2.66,;17.29,1.2,;18.77,.85,;20.25,.5,;19.12,2.33,;18.41,-.63,;15.42,3.17,;14.81,1.71,;13.66,.63,;12.11,.34,;11.84,1.86,;10.43,2.41,;9.17,1.51,;9.45,-.03,;10.88,-.61,;7.95,2.6,;6.39,2.52,;5.48,3.75,;3.97,3.6,;6.13,5.14,;7.66,5.34,;8.37,6.74,;9.51,7.78,;10.98,8.22,;12.52,8.08,;13.9,7.38,;14.93,6.21,;16.25,6.97,;15.45,4.69,;8.51,4.06,)| | ||
| Structure | 
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