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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559734 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.10±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559734 | |||
| n/a | |||
| Name | BDBM559734 | ||
| Synonyms: | WO2022109117, Example 79 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H33N3O6S | ||
| Mol. Mass. | 467.579 | ||
| SMILES | C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3nc(OCCOC(=O)N12)ccc3C |wD:1.0,3.3,9.29,(-.94,-5.15,;-.57,-3.68,;-1.54,-2.51,;-.73,-1.23,;-1.29,.18,;-2.8,.4,;-4.3,.62,;-3.01,-1.1,;-2.58,1.9,;.74,-1.6,;1.23,-.1,;2.27,1.13,;3.88,1.46,;5.21,2.29,;6.64,1.71,;6.85,.16,;5.55,-.68,;4.18,-.05,;7.96,-1.03,;7.22,-2.39,;7.94,-3.75,;7.07,-5.02,;5.77,-5.85,;4.23,-6.02,;2.75,-5.57,;1.55,-4.55,;.36,-5.49,;.84,-3.12,;9.5,-3.8,;10.24,-2.47,;9.52,-1.13,;10.34,.15,)| | ||
| Structure | 
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