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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559737 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.07±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559737 | |||
| n/a | |||
| Name | BDBM559737 | ||
| Synonyms: | WO2022109117, Example 82 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H29F2N3O6S | ||
| Mol. Mass. | 489.533 | ||
| SMILES | C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3nc(OCCOC(=O)N12)c(F)cc3F |wD:1.0,3.3,9.29,(-.98,-5.13,;-.61,-3.66,;-1.58,-2.49,;-.77,-1.2,;-1.33,.21,;-2.84,.42,;-4.34,.64,;-3.05,-1.08,;-2.62,1.93,;.7,-1.58,;1.19,-.08,;2.22,1.16,;3.84,1.48,;5.17,2.32,;6.6,1.74,;6.8,.18,;5.51,-.66,;4.14,-.02,;7.91,-1.01,;7.18,-2.37,;7.9,-3.73,;7.03,-5,;5.73,-5.83,;4.19,-6,;2.71,-5.54,;1.51,-4.53,;.31,-5.46,;.8,-3.09,;9.46,-3.77,;10.21,-5.09,;10.19,-2.45,;9.48,-1.1,;10.3,.18,)| | ||
| Structure | 
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