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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559747 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.13±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM559747 | |||
| n/a | |||
| Name | BDBM559747 | ||
| Synonyms: | WO2022109117, Example 92 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H31FN4O5S | ||
| Mol. Mass. | 470.558 | ||
| SMILES | C[C@@H]1C[C@H](NS(C)(=O)=O)[C@@H]2COC3CCC(CC3)c3ccc(F)c(NCCOC(=O)N12)n3 |wD:1.0,3.3,9.32,(16.35,5.9,;15.98,4.43,;16.95,3.26,;16.14,1.97,;16.7,.56,;18.21,.35,;19.71,.13,;18.42,1.85,;17.99,-1.16,;14.66,2.35,;14.18,.85,;13.14,-.39,;11.53,-.71,;10.2,-1.55,;8.77,-.97,;8.56,.59,;9.86,1.43,;11.23,.79,;7.45,1.78,;5.89,1.87,;5.17,3.22,;5.91,4.54,;5.16,5.86,;7.46,4.5,;8.34,5.77,;9.64,6.6,;11.18,6.77,;12.66,6.31,;13.86,5.3,;15.05,6.23,;14.56,3.86,;8.19,3.14,)| | ||
| Structure | 
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