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Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM559765 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | IP-One Assay | ||
| IC50 | 0.41±n/a nM | ||
| Citation |  L., BS; Ping, C; James, CD; Jian, L; T., RM; Li, X; Dexi, Y; Shishi, L 3-AMINO PYRROLIDINE AND PIPERIDINE MACROCYCLIC OREXIN RECEPTOR AGONISTS WIPOWO2022109117 Publication Date 5/27/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM559765 | |||
| n/a | |||
| Name | BDBM559765 | ||
| Synonyms: | WO2022109117, Example 108 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H33F2N3O7S | ||
| Mol. Mass. | 533.586 | ||
| SMILES | COc1cc2OCCCOC(=O)N3[C@H](C)C[C@H](NS(=O)(=O)C(F)F)[C@@H]3COC3CCC(CC3)c(c1)n2 |wD:16.16,13.13,24.24,(3.75,3.52,;4.63,2.28,;6.15,2.43,;6.8,3.81,;8.34,4.01,;9.05,5.41,;10.21,6.44,;11.68,6.88,;13.22,6.73,;14.6,6.02,;15.62,4.85,;16.94,5.61,;16.14,3.36,;17.6,3.79,;18.11,5.22,;18.46,2.53,;17.53,1.33,;17.96,-.13,;19.44,-.49,;19.8,.99,;19.08,-1.97,;20.92,-.85,;21.34,-2.31,;21.97,.25,;16.09,1.84,;15.48,.34,;14.32,-.73,;12.77,-1.01,;12.51,.51,;11.1,1.06,;9.83,.17,;10.11,-1.37,;11.53,-1.96,;8.62,1.27,;7.06,1.19,;9.19,2.72,)| | ||
| Structure | 
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