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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM561397 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Adenosine A2A Receptor Cyclic AMP GS Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Huang, T; Wang, X Pyrazolopyridines and triazolopyridines as A2A / A2B inhibitors US Patent US11390624 Publication Date 7/19/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
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| BDBM561397 | |||
| n/a | |||
| Name | BDBM561397 | ||
| Synonyms: | 3-(7-amino-4-(1-ethyl-1H-pyrazol-5-yl)-2-((6-methylpyridin-2-yl)methyl)-2H-pyrazolo[3,4-c]pyridin-5-yl)benzonitrile | US11390624, Example 11 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H22N8 | ||
| Mol. Mass. | 434.4958 | ||
| SMILES | CCn1nccc1-c1c(nc(N)c2nn(Cc3cccc(C)n3)cc12)-c1cccc(c1)C#N |(2.92,3.35,;1.78,2.32,;.32,2.8,;-.16,4.26,;-1.7,4.26,;-2.18,2.8,;-.93,1.9,;-.93,.36,;-2.26,-.41,;-2.26,-1.95,;-.93,-2.72,;-.93,-4.26,;.4,-1.95,;1.87,-2.43,;2.77,-1.18,;4.31,-1.18,;5.08,.15,;4.31,1.48,;5.08,2.82,;6.62,2.82,;7.39,1.48,;8.93,1.48,;6.62,.15,;1.87,.06,;.4,-.41,;-3.6,.36,;-3.6,1.9,;-4.93,2.67,;-6.27,1.9,;-6.27,.36,;-4.93,-.41,;-7.6,-.41,;-8.93,-1.18,)| | ||
| Structure | 
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