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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM561427 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Adenosine A2A Receptor Cyclic AMP GS Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Huang, T; Wang, X Pyrazolopyridines and triazolopyridines as A2A / A2B inhibitors US Patent US11390624 Publication Date 7/19/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
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| BDBM561427 | |||
| n/a | |||
| Name | BDBM561427 | ||
| Synonyms: | 3-(4-amino-7-(4-methyloxazol-5-yl)-2-(pyridin-2-ylmethyl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)-2-fluorobenzonitrile | US11390624, Example 41 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H15FN8O | ||
| Mol. Mass. | 426.4059 | ||
| SMILES | Cc1ncoc1-c1c(nc(N)c2nn(Cc3ccccn3)nc12)-c1cccc(C#N)c1F |(2.55,2.32,;1.09,2.8,;.61,4.26,;-.93,4.26,;-1.41,2.8,;-.16,1.9,;-.16,.36,;-1.49,-.41,;-1.49,-1.95,;-.16,-2.72,;-.16,-4.26,;1.17,-1.95,;2.64,-2.43,;3.54,-1.18,;5.08,-1.18,;5.85,.15,;5.08,1.48,;5.85,2.82,;7.39,2.82,;8.16,1.48,;7.39,.15,;2.64,.06,;1.17,-.41,;-2.83,.36,;-2.83,1.9,;-4.16,2.67,;-5.5,1.9,;-5.5,.36,;-6.83,-.41,;-8.16,-1.18,;-4.16,-.41,;-4.16,-1.95,)| | ||
| Structure | 
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