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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM561431 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Adenosine A2A Receptor Cyclic AMP GS Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Huang, T; Wang, X Pyrazolopyridines and triazolopyridines as A2A / A2B inhibitors US Patent US11390624 Publication Date 7/19/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
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| BDBM561431 | |||
| n/a | |||
| Name | BDBM561431 | ||
| Synonyms: | 3-(4-amino-2-((1-methyl-1H-pyrazol-3-yl)methyl)-7-(4-methyloxazol-5-yl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)benzonitrile | US11390624, Example 45 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H17N9O | ||
| Mol. Mass. | 411.4194 | ||
| SMILES | Cc1ncoc1-c1c(nc(N)c2nn(Cc3ccn(C)n3)nc12)-c1cccc(c1)C#N |(2.08,2.32,;.61,2.8,;.13,4.26,;-1.41,4.26,;-1.88,2.8,;-.64,1.9,;-.64,.36,;-1.97,-.41,;-1.97,-1.95,;-.64,-2.72,;-.64,-4.26,;.7,-1.95,;2.16,-2.43,;3.07,-1.18,;4.61,-1.18,;5.38,.15,;4.75,1.56,;5.9,2.59,;7.23,1.82,;8.64,2.44,;6.91,.31,;2.16,.06,;.7,-.41,;-3.3,.36,;-3.3,1.9,;-4.64,2.67,;-5.97,1.9,;-5.97,.36,;-4.64,-.41,;-7.3,-.41,;-8.64,-1.18,)| | ||
| Structure | 
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