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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A2a | ||
| Ligand | BDBM561434 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Adenosine A2A Receptor Cyclic AMP GS Assay | ||
| Ki | <10±n/a nM | ||
| Citation |  Huang, T; Wang, X Pyrazolopyridines and triazolopyridines as A2A / A2B inhibitors US Patent US11390624 Publication Date 7/19/2022 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A2a | |||
| Name: | Adenosine receptor A2a | ||
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44716.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P29274 | ||
| Residue: | 412 | ||
| Sequence: |
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| BDBM561434 | |||
| n/a | |||
| Name | BDBM561434 | ||
| Synonyms: | 3-(4-amino-7-(4-methyloxazol-5-yl)-2-(2-(pyridin-2-yl)ethyl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)benzonitrile | US11390624, Example 48 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H18N8O | ||
| Mol. Mass. | 422.442 | ||
| SMILES | Cc1ncoc1-c1c(nc(N)c2nn(CCc3ccccn3)nc12)-c1cccc(c1)C#N |(1.47,2.32,;.01,2.8,;-.47,4.26,;-2.01,4.26,;-2.48,2.8,;-1.24,1.9,;-1.24,.36,;-2.57,-.41,;-2.57,-1.95,;-1.24,-2.72,;-1.24,-4.26,;.1,-1.95,;1.56,-2.43,;2.47,-1.18,;4.01,-1.18,;4.78,.15,;6.26,.55,;7.35,-.54,;8.84,-.14,;9.24,1.34,;8.15,2.43,;6.66,2.03,;1.56,.06,;.1,-.41,;-3.9,.36,;-3.9,1.9,;-5.24,2.67,;-6.57,1.9,;-6.57,.36,;-5.24,-.41,;-7.91,-.41,;-9.24,-1.18,)| | ||
| Structure | 
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