| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
|---|
| Ligand | BDBM50418001 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | UCHL1 Biochemical IC50 Assay |
|---|
| IC50 | 55000±n/a nM |
|---|
| Citation |  Stockley, ML; Kemp, MI; Madin, A; Woodrow, MD Sulfonamide-substituted cyanopyrrolidines with activity as DUB inhibitors US Patent US11414402 Publication Date 8/16/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
|---|
| Name: | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |
|---|
| Synonyms: | Neuron cytoplasmic protein 9.5 | PGP 9.5 | PGP9.5 | UCH-L1 | UCHL1 | UCHL1_HUMAN | Ubiquitin thioesterase L1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 24819.03 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_974327 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHE
NFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSE
TEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMP
FPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA
|
|
|
|---|
| BDBM50418001 |
|---|
| n/a |
|---|
| Name | BDBM50418001 |
|---|
| Synonyms: | CHEMBL1672421 | US11414402, Example 6 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H13N3O2S |
|---|
| Mol. Mass. | 251.305 |
|---|
| SMILES | O=S(=O)(N[C@H]1CCN(C1)C#N)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
