Reaction Details |
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Target | External core antigen |
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Ligand | BDBM576349 |
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Substrate/Competitor | n/a |
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Meas. Tech. | PHH Natural Infection Assay |
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IC50 | 750±n/a nM |
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Citation | Hongying, Y; Bo, Z; Xiufang, Z AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION WIPOWO2022112205 Publication Date 6/2/2022 |
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More Info.: | Get all data from this article, Assay Method |
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External core antigen |
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Name: | External core antigen |
Synonyms: | C | HBEAG_HBVGB | HBeAg | Precore protein | p25 |
Type: | Protein |
Mol. Mass.: | 24103.68 |
Organism: | HBVgbn |
Description: | P89951 |
Residue: | 212 |
Sequence: | MQLFHLCLIISCSCPTVQASKLCLGWLLGMDIDPYKEFGASVELLSFLPSDFFPSVRDLL
DTASALYREALESPEHCSPNHTALRQAVLCWGELMTGCSWVGNNLEDPASRELVVNYVNT
NMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRR
RGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
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BDBM576349 |
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n/a |
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Name | BDBM576349 |
Synonyms: | WO2022112205, Example 5 |
Type | Small organic molecule |
Emp. Form. | C20H17ClN2O5S |
Mol. Mass. | 432.877 |
SMILES | Clc1ccc2oc(nc2c1)C12CC(C1)(C2)NC(=O)c1ccc(o1)S(=O)(=O)C1CC1 |
Structure |
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