| Reaction Details |
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 | Report a problem with these data |
| Target | Fibroblast growth factor receptor 2 |
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| Ligand | BDBM454191 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays |
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| EC50 | 11.0±n/a nM |
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| Citation |  Wurtz, NR; Shirude, PS Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists US Patent US11530183 Publication Date 12/20/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fibroblast growth factor receptor 2 |
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| Name: | Fibroblast growth factor receptor 2 |
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| Synonyms: | BEK | CD_antigen=CD332 | FGFR-2 | FGFR-2 Tyrosine Kinase | FGFR2 | FGFR2_HUMAN | Fibroblast growth factor receptor 2 (FGFR2) | Fibroblast growth factor receptor 2 precursor | KGFR | KSAM | Keratinocyte growth factor receptor | Keratinocyte growth factor receptor 2 | VEGF-receptor 2 and Fibroblast growth factor receptor 2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 92015.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21802 |
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| Residue: | 821 |
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| Sequence: | MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEV
RCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYF
MVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCP
AGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSI
NHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSK
YGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVL
PAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTK
RIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDK
LTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKM
IGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTF
KDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKT
TNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH
RMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYS
PSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
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| BDBM454191 |
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| n/a |
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| Name | BDBM454191 |
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| Synonyms: | US10717708, Example 82 | US11186544, Example 82 | US11530183, Example 82 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20Cl3N3O2 |
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| Mol. Mass. | 488.794 |
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| SMILES | Clc1ccc(NC(=O)N[C@@H]2CCCN(C2=O)c2ccc(cc2)-c2c(Cl)cccc2Cl)cc1 |r| |
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| Structure | 
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