| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type 1D |
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| Ligand | BDBM585139 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical CaMK1D Enzymatic Activity Assay |
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| IC50 | 28.0±n/a nM |
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| Citation |  Fischer, P; Fromont, C; Stevenson, B; Butterworth, S; Iacobini, G; Greco, G; Sanz, MG; Jones, H; Kaur, D Kinase inhibitors US Patent US11530193 Publication Date 12/20/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type 1D |
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| Name: | Calcium/calmodulin-dependent protein kinase type 1D |
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| Synonyms: | CAMK1D | CAMKID | CaM kinase I delta | KCC1D_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42916.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_586559 |
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| Residue: | 385 |
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| Sequence: | MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALK
GKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKD
ASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMST
ACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEF
DSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKN
FAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSS
SGVSGVGAERRPRPTTVTAVHSGSK
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| BDBM585139 |
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| n/a |
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| Name | BDBM585139 |
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| Synonyms: | US11530193, Example 52 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30N8O |
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| Mol. Mass. | 470.5694 |
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| SMILES | N[C@H]1CCCN(C1)c1ncc(C(N)=O)c(Nc2cc(cc(c2)C2(CCC2)C#N)C2(CCC2)C#N)n1 |r| |
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| Structure | 
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