| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 11 |
|---|
| Ligand | BDBM50273522 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Histone Deacetylase Assay I |
|---|
| IC50 | <500±n/a nM |
|---|
| Citation |  Zheng, X; Martin, MW; Ng, PY; Thomason, JR; Han, B; Rudnitskaya, A; Lancia, Jr., DR Isoindolines as HDAC inhibitors US Patent US11535607 Publication Date 12/27/2022 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 11 |
|---|
| Name: | Histone deacetylase 11 |
|---|
| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 39187.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q96DB2 |
|---|
| Residue: | 347 |
|---|
| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
|
|
|
|---|
| BDBM50273522 |
|---|
| n/a |
|---|
| Name | BDBM50273522 |
|---|
| Synonyms: | CHEMBL4127743 | US11535607, Example 12-1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H13F3N4O2 |
|---|
| Mol. Mass. | 362.3059 |
|---|
| SMILES | ONC(=O)c1cccc2CN(Cc12)c1nc2ccc(cc2[nH]1)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
