| Reaction Details |
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 | Report a problem with these data |
| Target | Inward rectifier potassium channel 2 |
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| Ligand | BDBM600748 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | thallium-flux assay |
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| IC50 | >30000±n/a nM |
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| Citation |  Swale, DR; Foil, LD Method for controlling hematophagous or sap-feeding arthropods US Patent US11632953 Publication Date 4/25/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Inward rectifier potassium channel 2 |
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| Name: | Inward rectifier potassium channel 2 |
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| Synonyms: | Cardiac inward rectifier potassium channel | IRK-1 | IRK1 | Inward rectifier K(+) channel Kir2.1 | KCNJ2 | KCNJ2_HUMAN | Potassium channel, inwardly rectifying subfamily J member 2 | hIRK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48281.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1515520 |
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| Residue: | 427 |
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| Sequence: | MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFIN
VGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK
ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVM
AKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEG
EYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEG
MVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARD
LAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRP
LRRESEI
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|
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| BDBM600748 |
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| n/a |
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| Name | BDBM600748 |
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| Synonyms: | US11632953, Compound 5 | VU0650730 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19N3O2 |
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| Mol. Mass. | 297.3517 |
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| SMILES | O=C(Cn1ncc2COCCc12)N1CCCc2ccccc12 |
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| Structure | 
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