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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine/threonine-protein kinase pim-1 | ||
| Ligand | BDBM602168 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Pim-1 Inhibitory Activity Assay | ||
| Ki | 0.044±n/a nM | ||
| Citation |  Inoue, M; Ogoshi, Y; Furukawa, T; Machida, T; Mitani, I; Harada, K; Nakagawa, Y; Yamaoka, N Tetrahydrobenzofurodiazepinone compound and pharmaceutical use thereof US Patent US11643417 Publication Date 5/9/2023 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine/threonine-protein kinase pim-1 | |||
| Name: | Serine/threonine-protein kinase pim-1 | ||
| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 35681.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P11309 | ||
| Residue: | 313 | ||
| Sequence: |
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| BDBM602168 | |||
| n/a | |||
| Name | BDBM602168 | ||
| Synonyms: | US11643417, Ex. No. 163 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H24F3N3O3 | ||
| Mol. Mass. | 435.4395 | ||
| SMILES | OCC1(CCC(CCN2CCNC(=O)c3oc4ccc(cc4c23)C(F)(F)F)CC1)C#N |(4.98,-1.15,;5.48,.31,;4.47,1.46,;3.31,.45,;1.85,.95,;1.55,2.46,;.1,2.96,;-1.06,1.94,;-2.52,2.44,;-2.7,3.97,;-4.01,4.78,;-5.46,4.26,;-5.96,2.8,;-7.49,2.62,;-5.13,1.51,;-5.76,.1,;-4.61,-.93,;-4.61,-2.47,;-3.28,-3.24,;-1.95,-2.47,;-1.95,-.93,;-3.28,-.16,;-3.6,1.35,;-.61,-3.24,;.72,-2.47,;-.61,-4.78,;.72,-4.01,;2.71,3.47,;4.17,2.98,;5.98,1.76,;7.49,2.06,)| | ||
| Structure | 
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