| Reaction Details |
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 | Report a problem with these data |
| Target | Granzyme B |
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| Ligand | BDBM605157 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| IC50 | 150±n/a nM |
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| Citation |  Bilcer, GM; Kelly, TA Granzyme B directed imaging and therapy US Patent US11667645 Publication Date 6/6/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Granzyme B |
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| Name: | Granzyme B |
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| Synonyms: | CGL1 | CSPB | CTLA1 | GRAB_HUMAN | GRB | GZMB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27735.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_469245 |
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| Residue: | 247 |
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| Sequence: | MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVL
TAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKR
TRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHY
YDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWI
KKTMKRY
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| BDBM605157 |
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| n/a |
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| Name | BDBM605157 |
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| Synonyms: | (1S,8S)-8-((S)-2-Benzoylamino-3- methyl-butyrylamino)-9-oxo-1,2,8,9- tetrahydro-7H-6-oxa-9a-aza- benzo[cd]azulene-1-carboxylic acid (1H-[1,2,3,]triazol-4-ylmethyl)-amide | US11667645, Compound C100 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H29N7O5 |
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| Mol. Mass. | 531.5631 |
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| SMILES | CC(C)[C@H](NC(=O)c1ccccc1)C(=O)N[C@H]1COc2cccc3C[C@H](N(c23)C1=O)C(=O)NCc1c[nH]nn1 |r| |
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| Structure | 
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