Reaction Details |
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Target | Sigma intracellular receptor 2 |
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Ligand | BDBM349365 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Competitive Radioligand Binding Assay |
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Ki | 5.00±n/a nM |
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Citation | Rishton, GM; Catalano, SM; Look, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent US11691947 Publication Date 7/4/2023 |
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More Info.: | Get all data from this article, Assay Method |
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Sigma intracellular receptor 2 |
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Name: | Sigma intracellular receptor 2 |
Synonyms: | S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97 |
Type: | Protein |
Mol. Mass.: | 20953.88 |
Organism: | Rattus norvegicus (Rat) |
Description: | Q5U3Y7 |
Residue: | 176 |
Sequence: | MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQ
EPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILF
EDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
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BDBM349365 |
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n/a |
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Name | BDBM349365 |
Synonyms: | US10207991, Ex. Cpd. No. 10 | US10611728, Example Compound 10 | US11691947, Example 10 |
Type | Small organic molecule |
Emp. Form. | C19H19Cl2NO2 |
Mol. Mass. | 364.266 |
SMILES | C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc3OCOc3cc2C1 |r| |
Structure |
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