| Reaction Details |
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 | Report a problem with these data |
| Target | Thymocyte selection-associated high mobility group box protein TOX |
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| Ligand | BDBM511481 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Kinase Activity Assay |
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| IC50 | 100000±n/a nM |
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| Citation |  deLong, MA; Carlson, E; Kopczynski, C; Sturdivant, JM; Lichorowic, C Isoquinoline-steroid conjugates and uses thereof US Patent US11691950 Publication Date 7/4/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Thymocyte selection-associated high mobility group box protein TOX |
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| Name: | Thymocyte selection-associated high mobility group box protein TOX |
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| Synonyms: | Thymus high mobility group box protein TOX |
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| Type: | Protein |
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| Mol. Mass.: | 57520.31 |
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| Organism: | Human |
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| Description: | O94900 |
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| Residue: | 526 |
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| Sequence: | MDVRFYPPPAQPAAAPDAPCLGPSPCLDPYYCNKFDGENMYMSMTEPSQDYVPASQSYPG
PSLESEDFNIPPITPPSLPDHSLVHLNEVESGYHSLCHPMNHNGLLPFHPQNMDLPEITV
SNMLGQDGTLLSNSISVMPDIRNPEGTQYSSHPQMAAMRPRGQPADIRQQPGMMPHGQLT
TINQSQLSAQLGLNMGGSNVPHNSPSPPGSKSATPSPSSSVHEDEGDDTSKINGGEKRPA
SDMGKKPKTPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPNATFGEVSKIVASMWD
GLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQPPQLINSKPSVFH
GPSQAHSALYLSSHYHQQPGMNPHLTAMHPSLPRNIAPKPNNQMPVTVSIANMAVSPPPP
LQISPPLHQHLNMQQHQPLTMQQPLGNQLPMQVQSALHSPTMQQGFTLQPDYQTIINPTS
TAAQVVTQAMEYVRSGCRNPPPQPVDWNNDYCSSGGMQRDKALYLT
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| BDBM511481 |
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| n/a |
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| Name | BDBM511481 |
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| Synonyms: | US11059789, Example 25 | US11691950, Example 25 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H50FN3O9 |
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| Mol. Mass. | 795.8916 |
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| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COC(=O)CCC(=O)OCc1ccc(cc1)[C@@H](CN)C(=O)Nc1ccc2cnccc2c1 |r,c:11,t:7| |
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| Structure | 
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