| Reaction Details |
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 | Report a problem with these data |
| Target | Epoxide hydrolase 1 |
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| Ligand | BDBM409005 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibitors of Soluble Epoxide Hydrolase (sEH) |
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| Ki | <0.050±n/a nM |
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| Citation |  Chiamvimonvat, N; Hammock, BD; Sirish, P Methods of improving cell-based therapy US Patent US11723929 Publication Date 8/15/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Epoxide hydrolase 1 |
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| Name: | Epoxide hydrolase 1 |
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| Synonyms: | EPHX | EPHX1 | EPOX | Epoxide hydrolase (EH) | Epoxide hydrolase (HsEH) | Epoxide hydrolase 1 | HYEP_HUMAN | Microsomal epoxide hydrolase |
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| Type: | Protein |
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| Mol. Mass.: | 52954.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07099 |
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| Residue: | 455 |
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| Sequence: | MWLEILLTSVLGFAIYWFISRDKEETLPLEDGWWGPGTRSAAREDDSIRPFKVETSDEEI
HDLHQRIDKFRFTPPLEDSCFHYGFNSNYLKKVISYWRNEFDWKKQVEILNRYPHFKTKI
EGLDIHFIHVKPPQLPAGHTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV
ICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQEFYIQGGDWGSLICTNMAQLVP
SHVKGLHLNMALVLSNFSTLTLLLGQRFGRFLGLTERDVELLYPVKEKVFYSLMRESGYM
HIQCTKPDTVGSALNDSPVGLAAYILEKFSTWTNTEFRYLEDGGLERKFSLDDLLTNVML
YWTTGTIISSQRFYKENLGQGWMTQKHERMKVYVPTGFSAFPFELLHTPEKWVRFKYPKL
ISYSYMVRGGHFAAFEEPELLAQDIRKFLSVLERQ
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| BDBM409005 |
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| n/a |
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| Name | BDBM409005 |
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| Synonyms: | US10377744, Compound No. 26 | US11123311, Compound 26 | US11723929, Compound 26 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23F4N3O3 |
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| Mol. Mass. | 405.3871 |
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| SMILES | CC[C@H](C)C(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)c(F)c1 |r| |
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| Structure | 
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