Reaction Details | |||
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Target | Interleukin-17F | ||
Ligand | BDBM617577 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | AlphaLISA Assay | ||
IC50 | 50.1±n/a nM | ||
Citation | MARTIN, BP; WESTERMANN, J; KERN, OT; HOLMES, AJ; MORRISON, A; KICZUN, M; AL MASRI, M; SMITH, A; HUXLEY, A IL-17A MODULATORS US Patent US20230286943 Publication Date 9/14/2023 | ||
More Info.: | Get all data from this article, Assay Method | ||
Interleukin-17F | |||
Name: | Interleukin-17F | ||
Synonyms: | Cytokine ML-1 | IL17F | IL17F_HUMAN | il-17f | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 18053.35 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q96PD4 | ||
Residue: | 163 | ||
Sequence: |
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BDBM617577 | |||
n/a | |||
Name | BDBM617577 | ||
Synonyms: | US20230286943, Example 45 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H33N7O2 | ||
Mol. Mass. | 463.5752 | ||
SMILES | CCn1nccc1C(=O)N[C@@H]([C@H]1CC[C@H](C)CC1)C(=O)Nc1ccc(cn1)-c1c(C)cnn1C |r,wU:14.15,wD:10.10,11.12,(3.55,-3.12,;5.02,-3.59,;6.16,-2.56,;7.67,-2.88,;8.44,-1.55,;7.41,-.4,;6,-1.03,;4.67,-.26,;4.67,1.28,;3.33,-1.03,;2,-.26,;2,1.28,;3.33,2.05,;3.33,3.59,;2,4.36,;2,5.9,;.67,3.59,;.67,2.05,;.67,-1.03,;.67,-2.57,;-.67,-.26,;-2,-1.03,;-2,-2.57,;-3.33,-3.34,;-4.67,-2.57,;-4.67,-1.03,;-3.33,-.26,;-6,-3.34,;-6.16,-4.87,;-5.02,-5.9,;-7.67,-5.19,;-8.44,-3.86,;-7.41,-2.71,;-7.73,-1.21,)| | ||
Structure |