| Reaction Details |
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 | Report a problem with these data |
| Target | B-cell lymphoma 6 protein |
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| Ligand | BDBM618584 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HTRF Assay |
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| IC50 | 2.57±n/a nM |
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| Citation |  Bellenie, BR; Cheung, KM; Davis, OA; Hoelder, S; Huckvale, R; Collie, G; Meniconi, M; Brennan, A; Lloyd, MG BCL6 INHIBITORS US Patent US20230287003 Publication Date 9/14/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| B-cell lymphoma 6 protein |
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| Name: | B-cell lymphoma 6 protein |
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| Synonyms: | B-cell lymphoma 5 protein | B-cell lymphoma 6 protein | BCL-5 | BCL-6 | BCL5 | BCL6 | BCL6_HUMAN | BCoR-BCL6 | LAZ3 | Protein LAZ-3 | ZBTB27 | ZNF51 | Zinc finger and BTB domain-containing protein 27 | Zinc finger protein 51 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78866.89 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117695 |
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| Residue: | 706 |
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| Sequence: | MASPADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSI
FTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLREGNIMAVMATAMYLQMEHVVDT
CRKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAF
APSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMPVANPFPKERALPCDSARPVPG
EYSRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAAPSARNAPYFPCDKAS
KEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPTESCSSKNACILQASG
SPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSPRAYTAPPACQPPMEP
ENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGS
QSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAFFCNECDCRFSEEASLKRHTLQT
HSDKPYKCDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTRIHSGEK
PYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGEKPYHC
EKCNLHFRHKSQLRLHLRQKHGAITNTKVQYRVSATDLPPELPKAC
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| BDBM618584 |
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| n/a |
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| Name | BDBM618584 |
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| Synonyms: | US20230287003, Example 13b |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28ClF2N7O3 |
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| Mol. Mass. | 572.006 |
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| SMILES | CN1C[C@H]2CC[C@H](N2c2ncc(Cl)c(Nc3ccc4n(C)c(=O)c5OCC(F)(F)[C@@H](Nc5c4c3)C3CC3)n2)C1=O |r,THB:8:7:2.1.38:4.5| |
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| Structure | 
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