| Reaction Details |
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 | Report a problem with these data |
| Target | von Hippel-Lindau disease tumor suppressor |
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| Ligand | BDBM621979 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Surface Plasmon Resonance (SP1R) |
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| Kd | 5500±n/a nM |
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| Citation |  YAMAKOSHI, S; ISHIZAWA, K; HAGIHARA, S; SAKATA, K; NIWA, Y; TANAKA, M HYDROXYPYRROLIDINE DERIVATIVE AND MEDICINAL APPLICATION THEREOF US Patent US20230312542 Publication Date 10/5/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| von Hippel-Lindau disease tumor suppressor |
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| Name: | von Hippel-Lindau disease tumor suppressor |
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| Synonyms: | Protein G7 | VHL | VHL_HUMAN | Von Hippel-Lindau disease tumor suppressor | Von Hippel-Lindau disease tumor suppressor protein (VBC) | pVHL |
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| Type: | Protein |
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| Mol. Mass.: | 24136.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P40337 |
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| Residue: | 213 |
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| Sequence: | MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPR
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD
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| BDBM621979 |
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| n/a |
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| Name | BDBM621979 |
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| Synonyms: | US20230312542, Example 17 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H32FN5O4 |
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| Mol. Mass. | 473.5404 |
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| SMILES | CN(Cc1ccccc1F)C(=O)c1c[nH]c(n1)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(C)=O)C(C)(C)C |r| |
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| Structure | 
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