| Reaction Details |
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 | Report a problem with these data |
| Target | YTH domain-containing family protein 1 |
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| Ligand | BDBM624898 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibition Assay Method |
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| Ki | 0.209±27 nM |
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| Citation |  Rana, TM BROAD SPECTRUM ANTI-CANCER COMPOUNDS US Patent US20230322715 Publication Date 10/12/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| YTH domain-containing family protein 1 |
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| Name: | YTH domain-containing family protein 1 |
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| Synonyms: | C20orf21 | DACA-1 | DF1 | Dermatomyositis associated with cancer putative autoantigen 1 | Synonyms=C20orf21 | YTHD1_HUMAN | YTHDF1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60886.98 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_120731 |
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| Residue: | 559 |
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| Sequence: | MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYY
PPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRF
NFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGM
NSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASK
PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQ
VAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAP
SVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKR
LDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIF
VKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYE
KRQEEEEVVRKERQSRNKQ
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| BDBM624898 |
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| n/a |
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| Name | BDBM624898 |
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| Synonyms: | US20230322715, Compound TR-YTH-18 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21N3 |
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| Mol. Mass. | 255.358 |
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| SMILES | CC(Nc1ccc(CN(C)C)cn1)c1ccccc1 |
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| Structure | 
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