| Reaction Details |
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 | Report a problem with these data |
| Target | YTH domain-containing family protein 2 |
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| Ligand | BDBM624900 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibition Assay Method |
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| Ki | 0.107±19 nM |
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| Citation |  Rana, TM BROAD SPECTRUM ANTI-CANCER COMPOUNDS US Patent US20230322715 Publication Date 10/12/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| YTH domain-containing family protein 2 |
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| Name: | YTH domain-containing family protein 2 |
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| Synonyms: | CLL-associated antigen KW-14 | DF2 | HGRG8 | High-glucose-regulated protein 8 | Renal carcinoma antigen NY-REN-2 | Synonyms=HGRG8 | YTHD2_HUMAN | YTHDF2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62346.00 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_118237 |
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| Residue: | 579 |
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| Sequence: | MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY
SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH
GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP
GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA
DIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPT
QGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSG
FGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSE
DDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYN
TCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQV
LKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK
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| BDBM624900 |
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| n/a |
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| Name | BDBM624900 |
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| Synonyms: | US20230322715, Compound TR-YTH-19 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18FN3 |
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| Mol. Mass. | 259.3219 |
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| SMILES | CN(C)Cc1ccc(NCc2ccc(F)cc2)nc1 |
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| Structure | 
|
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