| Reaction Details |
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 | Report a problem with these data |
| Target | Transcription factor SOX-18 |
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| Ligand | BDBM223296 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition of Sox18-DNA Binding Assay |
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| IC50 | 3803000±1000 nM |
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| Citation |  FRANCOIS, M; ZUEGG, J; OVERMAN, J; MAMIDYALA, SK; SALIM, AA; FONTAINE, FR; COOPER, MA; CAPON, RJ; ROBERTSON, AA COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT US Patent US20240002326 Publication Date 1/4/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Transcription factor SOX-18 |
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| Name: | Transcription factor SOX-18 |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 40895.30 |
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| Organism: | Human |
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| Description: | P35713 |
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| Residue: | 384 |
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| Sequence: | MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPR
SPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLG
KAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLPGLAPP
QPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDC
ALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLSPP
PEAPPLESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCP
EESSLISALSDASSAVYYSACISG
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| BDBM223296 |
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| n/a |
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| Name | BDBM223296 |
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| Synonyms: | Sm11 | US20240002326, Compound Sm11 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14O5 |
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| Mol. Mass. | 274.2687 |
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| SMILES | COc1ccc(OCC(=O)c2ccc(O)cc2O)cc1 |
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| Structure | 
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