| Reaction Details |
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 | Report a problem with these data |
| Target | Transcription factor SOX-18 |
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| Ligand | BDBM17636 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition of Sox18-DNA Binding Assay |
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| IC50 | 220000±68600 nM |
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| Citation |  FRANCOIS, M; ZUEGG, J; OVERMAN, J; MAMIDYALA, SK; SALIM, AA; FONTAINE, FR; COOPER, MA; CAPON, RJ; ROBERTSON, AA COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT US Patent US20240002326 Publication Date 1/4/2024 |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcription factor SOX-18 |
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| Name: | Transcription factor SOX-18 |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 40895.30 |
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| Organism: | Human |
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| Description: | P35713 |
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| Residue: | 384 |
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| Sequence: | MQRSPPGYGAQDDPPARRDCAWAPGHGAAADTRGLAAGPAALAAPAAPASPPSPQRSPPR
SPEPGRYGLSPAGRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLG
KAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKARRLEPGLLLPGLAPP
QPPPEPFPAASGSARAFRELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDC
ALRPFRAPYAPTELSRDPGGCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPYPGPLSPP
PEAPPLESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCP
EESSLISALSDASSAVYYSACISG
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| BDBM17636 |
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| n/a |
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| Name | BDBM17636 |
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| Synonyms: | 2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid | Arlef | CHEMBL23588 | Flufenamic acid | Nichisedan | US20240002326, Compound Flufenamic acid | US9271961, Flufenamic Acid |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10F3NO2 |
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| Mol. Mass. | 281.2299 |
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| SMILES | OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F |
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| Structure | 
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