| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Uracil nucleotide/cysteinyl leukotriene receptor |
|---|
| Ligand | BDBM646664 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | GPR17 cAMP Assay Protocol |
|---|
| IC50 | 20.0±n/a nM |
|---|
| Citation |  GALLEY, G; GOBBI, L; GUBA, W; MAZUNIN, D; PINARD, E; RICCI, A PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES US Patent US20240025883 Publication Date 1/25/2024 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Uracil nucleotide/cysteinyl leukotriene receptor |
|---|
| Name: | Uracil nucleotide/cysteinyl leukotriene receptor |
|---|
| Synonyms: | GPR17 | GPR17_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41013.71 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1353471 |
|---|
| Residue: | 367 |
|---|
| Sequence: | MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENM
LFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHF
SGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLAC
AFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCY
LLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQ
RILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESS
LSAKSEL
|
|
|
|---|
| BDBM646664 |
|---|
| n/a |
|---|
| Name | BDBM646664 |
|---|
| Synonyms: | N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-2-yl]-1H- pyrrolo[3,2-h]quinoline-3- sulfonamide | US20240025883, Example 169 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H17F2N5O4S |
|---|
| Mol. Mass. | 449.431 |
|---|
| SMILES | COc1nc(NS(=O)(=O)c2c[nH]c3c2ccc2cccnc32)nc(OC)c1CC(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
