| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM11020 |
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| Substrate/Competitor | BDBM10990 |
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| Meas. Tech. | MAO Inhibition Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | >1000000±n/a nM |
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| Comments | no inhibition |
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| Citation |  Hubalek, F; Binda, C; Khalil, A; Li, M; Mattevi, A; Castagnoli, N; Edmondson, DE Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. J Biol Chem280:15761-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA) |
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| Type: | Protein |
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| Mol. Mass.: | 59689.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21397 |
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| Residue: | 527 |
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| Sequence: | MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
VPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
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| BDBM11020 |
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| BDBM10990 |
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| Name | BDBM11020 |
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| Synonyms: | 1,4-diphenyl-2-butene (DPB) | [(2E)-4-phenylbut-2-en-1-yl]benzene |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16 |
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| Mol. Mass. | 208.2982 |
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| SMILES | C(\C=C\Cc1ccccc1)c1ccccc1 |
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| Structure | 
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