| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM321259 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay to Sigma Receptors |
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| Ki | 3.70±n/a nM |
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| Citation |  Melnyk, P; Vermersch, P; Carato, P; Oxombre-Vanteghem, B; Zephir, H; Donnier-Marechal, M Compounds, pharmaceutical composition and their use in treating neurodegenerative diseases US Patent US10179761 Publication Date 1/15/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM321259 |
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| n/a |
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| Name | BDBM321259 |
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| Synonyms: | N-[3-(benzylmethylamino)propyl]-4-propylbenzamide | US10179761, Compound 3.1.2 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28N2O |
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| Mol. Mass. | 324.4598 |
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| SMILES | CCCc1ccc(cc1)C(=O)NCCCN(C)Cc1ccccc1 |
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| Structure | 
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