| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 [134-239] |
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| Ligand | BDBM321424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | IC50 measurements for inhibitors using BRD9 AlphaLisa Binding Assay |
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| IC50 | 4.00±n/a nM |
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| Citation |  Albrecht, BK; Bellon, SF; Burdick, DJ; Cote, A; Crawford, T; Dakin, LA; Hsiao-Wei Tsui, V; Hewitt, MC; LeBlanc, Y; Magnuson, SR; Nasveschuk, CG; Romero, FA; Tang, Y; Taylor, AM; Wang, S Therapeutic compounds and uses thereof US Patent US10183009 Publication Date 1/22/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 9 [134-239] |
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| Name: | Bromodomain-containing protein 9 [134-239] |
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| Synonyms: | BRD9 | BRD9 (aa 134-239) | BRD9_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12286.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H8M2[134-239] |
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| Residue: | 106 |
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| Sequence: | AENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVAN
EYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
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| BDBM321424 |
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| n/a |
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| Name | BDBM321424 |
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| Synonyms: | 6-[(E)-but-2-enyl]-4-[2,5-dimethoxy-4-(morpholine-4-carbonyl)phenyl]-2-methyl-1H-pyrrolo[2,3-c]pyridin-7-one | US10183009, Example 108 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N3O5 |
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| Mol. Mass. | 451.5149 |
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| SMILES | COc1cc(c(OC)cc1C(=O)N1CCOCC1)-c1cn(C\C=C\C)c(=O)c2[nH]c(C)cc12 |
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| Structure | 
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