| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 [134-239] |
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| Ligand | BDBM321432 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | IC50 measurements for inhibitors using BRD9 AlphaLisa Binding Assay |
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| IC50 | 4.00±n/a nM |
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| Citation |  Albrecht, BK; Bellon, SF; Burdick, DJ; Cote, A; Crawford, T; Dakin, LA; Hsiao-Wei Tsui, V; Hewitt, MC; LeBlanc, Y; Magnuson, SR; Nasveschuk, CG; Romero, FA; Tang, Y; Taylor, AM; Wang, S Therapeutic compounds and uses thereof US Patent US10183009 Publication Date 1/22/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 9 [134-239] |
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| Name: | Bromodomain-containing protein 9 [134-239] |
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| Synonyms: | BRD9 | BRD9 (aa 134-239) | BRD9_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12286.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H8M2[134-239] |
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| Residue: | 106 |
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| Sequence: | AENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVAN
EYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSK
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| BDBM321432 |
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| n/a |
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| Name | BDBM321432 |
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| Synonyms: | (E)-6-(but-2-en-1-yl)-4-(3-chloro-4-(piperazine-1-carbonyl)phenyl)-2-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one | US10183009, Example 116 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25ClN4O2 |
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| Mol. Mass. | 424.923 |
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| SMILES | C\C=C\Cn1cc(-c2ccc(C(=O)N3CCNCC3)c(Cl)c2)c2cc(C)[nH]c2c1=O |
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| Structure | 
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