| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Progesterone receptor |
|---|
| Ligand | BDBM332401 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Progesterone Receptor Fluorescence Polarization Assay |
|---|
| IC50 | 251±n/a nM |
|---|
| Citation |  Turnbull, PS; Cadilla, R Chemical compounds US Patent US10196353 Publication Date 2/5/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Progesterone receptor |
|---|
| Name: | Progesterone receptor |
|---|
| Synonyms: | NR3C3 | Nuclear receptor subfamily 3 group C member 3 | PGR | PR | PRGR_HUMAN | progesterone |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 98979.52 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P06401 |
|---|
| Residue: | 933 |
|---|
| Sequence: | MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLF
PRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLA
PSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAA
AHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGK
PRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTV
MDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPD
CAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLG
PPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPC
KAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPP
YLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHN
YLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPV
GVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQ
LGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAP
DLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQ
FEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRA
LSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
|
|
|
|---|
| BDBM332401 |
|---|
| n/a |
|---|
| Name | BDBM332401 |
|---|
| Synonyms: | US10196353, Example 12 | US11299457, Example 12 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H19F3N2O |
|---|
| Mol. Mass. | 324.3408 |
|---|
| SMILES | CCCc1cc2c(c(ccc2n1CC(C)(C)O)C#N)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
