Reaction Details | |||
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Target | Monocarboxylate transporter 4 | ||
Ligand | BDBM345268 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Assay 3: MCT4-Mediated Lactate Transport in MDA-MB-231 Breast Cancer Cells | ||
IC50 | 30.0±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Monocarboxylate transporter 4 | |||
Name: | Monocarboxylate transporter 4 | ||
Synonyms: | MCT 4 | MCT3 | MCT4 | MOT4_HUMAN | SLC16A3 | Solute carrier family 16 member 3 | ||
Type: | PROTEIN | ||
Mol. Mass.: | 49474.36 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_104604 | ||
Residue: | 465 | ||
Sequence: |
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BDBM345268 | |||
n/a | |||
Name | BDBM345268 | ||
Synonyms: | 2-[[1-[(2-Chlorophenyl)methyl]-5-(3- methoxyphenyl)pyrazol-3-yl]methoxy]-2- methyl-propanoic acid 1H NMR (CDCl3, 400 MHz) $#948; 1.58 (s, 6H), 3.68 (s, 3H), 4.62 (s, 2H), 5.46 (s, 2H), 6.42 (s, 1H), 6.74-6.81 (m, 2H), 6.82- 6.88 (m, 1H), 6.89-6.94 (m, 1H), 7.15- 7023 (m, 2H), 7.26-7.37 (m, 2H). | US10202350, Example 14 | US10214492, Example 14 | US11292767, Example 14 | US11724989, Example 14 | ||
Type | Small organic molecule | ||
Emp. Form. | C22H23ClN2O4 | ||
Mol. Mass. | 414.882 | ||
SMILES | COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1Cl | ||
Structure | ![]() |