| Reaction Details |
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 | Report a problem with these data |
| Target | Fascin |
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| Ligand | BDBM350112 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Chemical Library Screens and Analysis |
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| IC50 | 2000±n/a nM |
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| Citation |  Huang, X; Shue, CY Methods for inhibiting fascin US Patent US10208043 Publication Date 2/19/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fascin |
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| Name: | Fascin |
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| Synonyms: | 55 kDa actin-bundling protein | FAN1 | FSCN1 | FSCN1_HUMAN | HSN | SNL | Singed-like protein | p55 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54533.89 |
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| Organism: | Homo sapiens (human) |
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| Description: | n/a |
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| Residue: | 493 |
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| Sequence: | MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAV
CLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLS
CFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLA
FQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTL
KAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDR
DTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKN
GQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFND
GAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKA
SAETVDPASLWEY
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| BDBM350112 |
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| n/a |
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| Name | BDBM350112 |
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| Synonyms: | (Z)-N-(3-(1H-1,2,4-triazol- 3-ylthio)-4-oxonaphthalen- 1(4H)-ylidene) benzenesulfonamide | US10208043, # 13 | US10941146, # 13 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H12N4O3S2 |
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| Mol. Mass. | 396.443 |
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| SMILES | O=C1C(Sc2nc[nH]n2)=CC(=NS(=O)(=O)c2ccccc2)c2ccccc12 |w:11.12,c:9| |
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| Structure | 
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