| Reaction Details |
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 | Report a problem with these data |
| Target | Fascin |
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| Ligand | BDBM350120 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Chemical Library Screens and Analysis |
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| IC50 | 1200±n/a nM |
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| Citation |  Huang, X; Shue, CY Methods for inhibiting fascin US Patent US10208043 Publication Date 2/19/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fascin |
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| Name: | Fascin |
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| Synonyms: | 55 kDa actin-bundling protein | FAN1 | FSCN1 | FSCN1_HUMAN | HSN | SNL | Singed-like protein | p55 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54533.89 |
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| Organism: | Homo sapiens (human) |
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| Description: | n/a |
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| Residue: | 493 |
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| Sequence: | MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAV
CLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLS
CFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLA
FQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTL
KAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDR
DTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKN
GQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFND
GAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKA
SAETVDPASLWEY
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| BDBM350120 |
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| n/a |
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| Name | BDBM350120 |
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| Synonyms: | 5-(3-chlorobenzyl)-1-(2- hydroxyethyl)-1H- pyrazol[3,4-d]pyrimidin- 4(5H)-one | US10208043, # 21 | US10941146, # 21 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H13ClN4O2 |
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| Mol. Mass. | 304.732 |
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| SMILES | OCCn1ncc2c1ncn(Cc1cccc(Cl)c1)c2=O |
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| Structure | 
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